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Acharya et al., Figure 3 shows the results of a regression analysis of diabetic patients and control subjects, segregated into four groups based on vitamin B 12 deficiency and oxidative stress

VolekJSFreidenreichDJSaenzCKuncesLJCreightonBCBartleyJMet alMetabolic characteristics of keto-adapted ultra-endurance runners

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Future studies examining protein expression and activation, such as Western blot analysis of phosphorylated Akt and PI3K, are warranted to confirm the mechanistic effects of DHA and Vildagliptin on the SIRT1/Akt/PI3K pathway in insulin-sensitive tissues such as skeletal muscle, liver, and adipose tissue to strengthen mechanistic and translational relevance