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Preliminary in vitro antisickilng properties of crude juice extracts of Persia Americana , citrus sinensis, Carica papaya and Ciklavit

Sooriyamoorthy T, Leslie SW

Dihexa is reported to be active at picomolar concentrations in synaptogenesis assaysapproximately 10,00010,000,000-fold more potent than BDNF (brain-derived neurotrophic factor) in some in vitro measures, though this comparison involves different assay conditions and should not be taken as a direct clinical equivalence claim

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Prior to measurements, cells were washed with unbuffered medium once, immersed in 500 mL of unbuffered medium, and incubated in the absence of CO 2 for 1 h