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In GRXC2, disulfide formation within the CPYC motif revealed a similar midpoint redox potential between 220 and 230 mV upon DTT/dithiane treatment, while HsGRX1 was barely oxidized by dithiane (Supplementary Fig

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In some embodiments, the formulations or compositions described herein are liquids and are administered via narrow gauge needles or cannulas (e.g., 22 gauge needle, 25 gauge needle, or cannula), minimizing damage to the tympanic membrane upon administration

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