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In: Burks AW, Holgate ST, O'Hehir RE, et al, eds

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Combined with reduced levels of OPG and higher levels of collagen type V, these results suggested that cigarette smoke exposure caused an increase in osteoblast apoptosis and bone resorption, leading to increased bone fragility

Firstly, the product encourages people to litter, or at least care less about disposing of their cigarettes properly, and the introduction of non-native tree species to random areas is ecologically problematic