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Several HDT drugs used in the treatment of TB, including statins, macrocyclic lactones, and TKI, have received approval by the US Food and Drug Administration for other clinical applications, underscoring their favorable safety profiles

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Moreland LW, Cannella A (2023): General principles of management of rheumatoid arthritis in adults

309 METTL3 also represses autophagy in ischemic heart disease by methylating TFEB mRNA, decreasing its stability and nuclear translocation, thereby impairing lysosomal biogenesis and exacerbating myocardial injury during hypoxiareoxygenation

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