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Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)
Pucci ND, Marchini GS, Mazzucchi E, et al
Some studies report higher glutathione levels and antioxidant capacity in postmenopausal women versus premenopausal women
NONSTEROIDAL ANTI-INFLAMMATORY DRUGS MECHANISM OF ACTION The nonsteroidal anti-inflammatory drugs comprise a large family of weak acidic drugs whose pharmacological effects result primarily from the inhibition of cyclooxygenase (COX) , an enzyme that catalyzes the first step in the synthesis of prostaglandins from arachidonic acid and other precursor fatty acids (see Chapter 26)
Plant Physiol Biochem 92:110 Jalil SU, Ahmad I, Ansari MI (2017) Functional loss of GABA transaminase (GABA-T) expressed early leaf senescence under various stress conditions in Arabidopsis thaliana
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