XF: Conceptualization, Writing original draft
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Chromatographic separation was carried out on a COSMOCORE C18 column (4.6 mm i.d
Introduction Cysteine, a sulfhydryl-containing proteinogenic amino acid essential for the human body, is employed in a variety of metabolic pathways, such as the regulation of reduced glutathione (GSH), a major endogenous antioxidant molecule and the generation of sulfur-containing biomolecules such as hydrogen sulfide (H 2 S), taurine, coenzyme A and biotin ( Figure 1 ) ( Figure 1 Cysteine metabolism in cancer and tumor microenvironment It is increasingly noted that altered levels of amino acids including cysteine in the tumor microenvironment, by uptake or processing of both intracellular and extracellular regions, have emerged as potential markers of tumor progression
Subcutaneous administration of sodium lactate solution promotes antitumor immunity through CM8 + T cells and sensitizes immunotherapy in CRC, NSCLC and melanoma mouse models