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High-dose vitamin B12 supplements taken concurrently with the injection may lead to excessive B12 levels, though toxicity from vitamin B12 excess is extremely rare due to its water-soluble nature and efficient renal excretion

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GHK-Cu modulates several genes involved in iron transport and storage, likely through the intimate connection between copper and iron metabolism (copper-dependent ceruloplasmin is essential for iron release from cells)

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Nishiyama, M., Skoultchi, A

Aravind L et al (2005) The many faces of the helix-turn-helix domain: transcription regulation and beyond