The relationship among GSH depletion, ferroptosis, and senescence has not been reported
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To illustrate, a 300 mg OLAI dose injected every 14 days can be calculated to provide an approximate zero-order oral dosing rate of 20 mg/day by dividing the injected dose by the number of days in the injection interval
J Neural Transm (Vienna) 116:15511560 Hoffmann C, Evcman S, Neumaier F, Zlatopolskiy BD, Humpert S, Bier D, Holschbach M, Schulze A, Endepols H, Neumaier B (2021) [18F] ALX5406: a brain-penetrating prodrug for GlyT1-specific PET imaging
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