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However, owing to their susceptibility to internal instability and the complexity of the biological environment, they are not ideal for widespread use [91]

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On the other hand, hydrogels are crafted from biomimetic materials and categorized as naturally derived, synthetic, or hybrid hydrogels based on their origins and compositions [256]

All experiments were approved by the Ethics Committee of the Plastic Surgery Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China