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Plant Physiol 129:460468 Paulose B, Chhikara S, Coomey J, H-I Jung, Vatamaniuk O, Dhankher OP (2013) A -glutamyl cyclotransferase protects Arabidopsis plants from heavy metal toxicity by recycling glutamate to maintain glutathione homeostasis

Together, these compounds accelerate hepatic fat metabolism through two primary pathways: enhanced methylation (which supports detoxification and cellular energy production) and lipotropic action (mobilising fat from hepatocytes and transporting it to mitochondria for oxidation)

Aging, diabetes, obesity, liver disease, chronic infections, pollution exposure, alcohol intake, and long-term medication use accelerate this depletion

For example, GLP-1 receptor agonists like semaglutide have become popular for their weight loss and glycemic benefits

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