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Mangiferin, a polyphenolic compound found in mangoes, used in an in vivo study on RA-induced DBA-1/J male mice reported downregulation of IL-1, IL-6, and TNF-, inhibited NF- signaling, and activated extracellular signal regulated kinase 1/2 (ERK1/2) (112)

2008, Apr, 23;1126(1):27275 Jov M, Portero-Otn M, Naud A, Ferrer I, Pamplona R

There was a significant decrease in GPX4 expression and an increase in ACSL4 expression in OA-damaged tissue (Fig

Antioxidative action in macrophage Cellular uptake Raw 264.7 cells were treated with LPS (10 ppm) for 2 days, aiming to promoting their polarization toward M1 phenotype

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This, in turn, would drive oxidatively induced cell death and increase barrier dysfunction and T2 inflammation, potentially identifying a mechanism by which viruses cause asthma exacerbations