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It is typically found in the brain and easily passes the blood-brain barrier

The Comprehensive Pharmacology Reference

In 2009, Elif Tatlidede et al

In addition, high-dose or prolonged anabolic steroid use has been linked to hepatic abnormalities, including rare cases of benign liver tumors or hepatic peliosis, and even malignant liver tumors, although such effects are uncommon with the doses used in therapeutic testosterone replacement

Qu F, Geng R, Liu Y, et al

UK Health Secretary Wes Streeting said: "I trust doctors over President Trump, frankly, on this." As with any pain-relieving medicine, it should be used at the lowest effective dose, for the shortest possible time and as infrequently as possible