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Currently, there is limited expertise within the sports medicine community regarding peptides such as BPC-157, and uncertainty surrounding their clinical application remains widespread

Whereas the monomers and the protofilaments are harmless, the oligomers are cytotoxic and induce cell death in primary neuronal cells, fibroblasts, and neuroblastoma cells [69]

The answer lies in gene expression

Tahara N, Tahara A, Honda A, et al

Kar et al., 2014), thus, it might be difficult to predict the toxicity directly from the structure

During the synthesis process, the reaction conditions such as temperature, pH value and reagent concentration need to be precisely controlled