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Glutathione can also cause changes to gene expression, DNA and protein synthesis, cell division and growth, and programmed cell death (apoptosis)

Figure S2), slightly enhanced proteomic reactivity was observed from the BDHI-containing fragments

While the precise mechanisms linking these metabolic alterations to fibrotic remodeling remain to be fully elucidated, current studies strongly support amino acid metabolism as a central regulatory axis in fibrosis initiation and progression

They also found no weight loss and normal biochemical markers compared to controls (Ombredane et al., 2021)

Despite the novelty of the current study regarding the effect of high dose NAC, it bears the limitations of a relatively small sample size and the inability to use placebo

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