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GHK-Cu has extensive dermatological research demonstrating collagen synthesis enhancement, though direct application to varicose veins remains largely theoretical extrapolation from wound healing data

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Promotes hair growth and thickness by increasing follicle size, reducing inflammation, and inhibiting 5-alpha reductase to reduce DHT

Generally, these variation peptides are found in parts per million in active technologies that topical products claim to include at high percentages but the final concentration of the variation peptides in topical products is generally less than 0.01% and these peptides would then have to be converted to even smaller amounts of pure copper peptides within the skin

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Pyakurel P, Shin M, Venton BJ (2018) Nicotinic acetylcholine receptor (nAChR) mediated dopamine release in larval Drosophila melanogaster