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doi:10.1016/j.neuroimage.2016.07.056 110

Repeated freeze-thaw cycles degrade the peptide and should be avoided

The activity of these enzymes is enhanced by a variety of chemicals, including caffeine[40, 41] and anticonvulsant drugs[42], and it is well known that co-ingestion of these drugs with APAP can greatly enhance the toxicity of APAP