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SIBO SIBO is a disease in which the number of bacteria in the small intestine increases abnormally, resulting in the production of large amounts of hydrogen, methane, and SCFAs, thereby causing symptoms, such as bloating and diarrhea ( 4 ) and hydrogen (H 2 ) exhalation testing are commonly used to further clarify the diagnosis (Pimentel et al., 2020)

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This could be every 2-4 weeks, or even monthly, depending on how your body responds