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These data support an effect of IL-13 to decrease total and reduced GSH through high 15LO1, PEBP1, and GPX4 activity, which is partially compensated by (a) increased expression/activity of SLC7A11 to enhance new intracellular GSH production and (b) increased export of GSSG

As observed previously 13 , the putative flavan-3,3,4-triol ( 4 ) was not stable during purification, and confirmatory time-course experiments showed almost complete degradation of the intermediate ( 4 ) within 24 h (Extended Data Fig

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Clearly, the accuracy of the concentration measurement at these very low solubilities is quite critical

Lysine (Lys): Contributes to protein stability and folding

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