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Shoulder pain has many causes, including referred pain from the cervical spine, thoracic outlet syndrome, and cardiac conditions (especially left shoulder pain)
Some providers view the B6 component as an added benefit for patients who experience mood changes during significant weight loss and caloric restriction
rather, there is a constellation of findings
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Increased expression of NLRP3 and caspase-1 genes in peripheral blood mononuclear cells (PBMC) and elevated protein levels of NLRP3, caspase-1, and IL-1B in the blood plasma were found to correlate with PD severity (40), further supporting the perception of PD as a chronic systemic inflammatory disease
