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Recent reviews have outlined the many environmental factors that are associated with ASD and have described how polymorphisms in specific genes can combine with the environment to cause neurodevelopmental problems (15)

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A.Salto-TellezM.Laurent-PuigP.BardelliA.RolfoC.TaberneroJ.et al (2018)

Table 2 illustrates the common AEs across the entire study (up to week 48, including the follow-up period).8 Integrated safety analysis According to an integrated safety analysis25 of data from the ALLEGRO-2a, ALLEGRO-2b/3, and ALLEGRO-LT trials, ritlecitinib was well tolerated in patients with AA