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Interactions with Medications and Substances Alcohol and Caffeine: Regular consumption of alcohol may interfere with the body's ability to absorb vitamin B12, potentially diminishing the efficacy of the injection and leading to suboptimal relief from deficiency symptoms

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10.1007/s00787-011-0203-3 38 SachdevP

Recommended Starting Dose of Retatrutide Phase 2 trial protocols typically initiated retatrutide at 2 mg once weekly via subcutaneous injection, allowing gradual physiological adaptation before dose escalation