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Powell SB, Sejnowski TJ, Behrens MM

Identifying biological correlates of successful treatments, at the cellular level, could advance our understanding of the mechanisms underlying remission, and pave the way for the development of novel treatment options

Figure 8 According to Peng et al., sophoridine could mediate the MAPK signaling pathway, enhance the expression of estrogen-related receptor gamma (ESRRG) to promote -catenin degradation, and inhibit the repair of double-stranded DNA breaks to caused cell cycle arrest at the G2/M phase, thereby lowering GC cell survival and increasing the efficiency of cisplatin

Hambrecht R, Wolf A, Gielen S, Linke A, Hofer J, Erbs S, et al

Muller WE, Pedigo NW Jr

& Yamanaka, K