Although currently mostly in preclinical studies, this co-delivery strategy is expected to gradually move toward clinical application as delivery systems improve and more pharmacokinetic/toxicological data accumulate (Table 4)
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Science 308, 13141318
Experiments can be conducted in a variety of environments (vacuum, steam, fumes), with two operation modes (contact and intermittent contact) available
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What this basically means is that the ordinary neurochemicals needed within the sympathetic nervous system can go on to stimulate hyper-excitable sensory cells in the DRG, and this produces the sensation of pain