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With the use of the ASOs to target the SCN1A NAT, one study was effectively able to rescue the sense SCN1A gene expression, ameliorate neuronal excitability and seizures in a mouse model of DSan effect that almost entirely recapitulates the rescued phenotypes observed via CRISPRa treatment [74, 75]

Composition of Liposomal L-Glutathione and Vitamin C Purified water, Glycerol, Phospholipids, Mango flavor, Dragon fruit flavor, Natural preservatives, Sea buckthorn extract, Rosemary extract, Acidity regulator, Citric acid monohydrate

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Murray CJ, Rosenfeld LC, Lim SS, Andrews KG, Foreman KJ, et al