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Both NAPQI and ROS cause mitochondrial DNA damage, activation of the JNK signaling pathway, which further amplifies the mitochondrial ROS production, and causes the mitochondrial permeability transition (MPT) pore to open (Iorga et al., 2017)

Neurochem Res 33:14101418 Rana S, Dringen R (2007) Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes

In non-diabetics, metformin may prolong the effects of flu vaccines by maintaining the survival of immune cells

It plays a central role in maintaining cellular function

When converted to CFU/culture ( C ) the cell count for suspended culture and biofilm was 2.510 11 and 2.010 11 , respectively, which was not significantly different by unpaired, two-tailed t -test

doi: 10.1007/s13238-015-0153-5 140 DangwalSThumT