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Optimal Timing and Dosing: Determining the ideal ratio, frequency, and duration of doses may optimize advantages while lowering receptor fatigue or tolerance [8]

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Long-term NAD + protocols have also been linked to improvements in transepidermal water loss (TEWL), reduced sensitivity to chemical and mechanical stress, and a more balanced skin microbiome

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Data availability The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request