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GHK treatment significantly improved collagen deposition, and MMP-9/TIMP-1 imbalances in lung tissue and also reduced TNF-, IL-6 expression in bronchoalveolar lavage fluid (BALF) and MPO in lung extracts

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extended this further, demonstrating KPV's therapeutic benefit in colitis-associated cancer models, with the PepT1 mechanism identified as the critical therapeutic pathway.5 Why Oral Delivery Works Most gut-targeted peptides face a delivery problem: they degrade before reaching the intestinal epithelium

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