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Furthermore, it was shown that curcumin has been found to significantly reduce H3ac levels in the IL-6 promoter as well as IL-6 mRNA expression in RA synovial fibroblasts (RASFs) (Makuch et al., 2021

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Toxicol Appl Pharmacol 2010;243:96103 [DOI] [PubMed] [Google Scholar] 65.Yang J, Yuan L, Liu F, Li L, Liu J, Chen Y, Lu Y, Yuan Y.Molecular mechanisms and physiological functions of autophagy in kidney diseases

As indicated by the designations, the A-beta subunit determines specificity for ADP/ATP and the G-beta for GDP/GTP