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A synergistic relationship exists between Sem and vitamin A, which helps control thyroid hormone metabolism and improves the conversion of T4 to T3 [73]
Although it cannot yet be determined whether vitamin B 12 deficiency plays a causal role in depression, it may be beneficial to screen for vitamin B 12 deficiency in older individuals as part of a medical evaluation for depression
8 This study also had several limitations, including a small sample size, short study duration, and absence of existing data on optimal dosing
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