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DSIP has been shown to influence neurotransmitter levels, including serotonin (5-HT), glutamate, dopamine, and melatonin, which are crucial for sleep regulation 2

doi:10.1002/nbm.2772, PMID: 22281935 Puri BK, Agour M, Gunatilake KD, Fernando KA, Gurusinghe AI, Treasaden IH (2009) An in vivo proton neurospectroscopy study of cerebral oxidative stress in myalgic encephalomyelitis (chronic fatigue syndrome)

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The perception of B12 shots as 'energy boosters' largely stems from the dramatic improvement seen when treating genuine deficiency, where fatigue is a cardinal symptom

Novel therapeutic effects in rat spinal cord injuries: recovery of the definitive and early spinal cord injury by the administration of pentadecapeptide BPC 157 therapy