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Increased total Nrf2 and phosphorylated Nrf2 protein levels in cortical tissue, and elevated Nrf2/NeuN and p-Nrf2/NeuN-positive neuron counts

The high suboptimal level is between optimal and where the nutrient becomes toxic

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Cobalife VB12 Plus Selenium injection (2 mg/mL hydroxocobalamin and 4 mg/mL selenium as sodium selenate) treats and controls Vitamin B12 and selenium deficiency in cattle and sheep for two to six months, depending on the severity of the deficiency