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If you are deficient, your cells are essentially starving for energy, leading to that heavy, lead-like fatigue

1 2 European Journal of Organic Chemistry

Unfortunately, the exact interconnections are not yet fully understood

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[3] [4] It is given by injection into a muscle or vein, [2] by pill or sublingually

For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)