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This is why it is so important that you take a vitamin B12 supplement daily, or get vitamin B12 injections routinely

The benefits are acute but also build over a few weeks

B12 injections may contribute to improved cognitive function, memory retention, and overall mental clarity

Frontiers in Pharmacology, 12, 627533

Aging and longevity: Preclinical work links MOTS-C to improved metabolic responses to aging, enhanced stress adaptation, and potential longevity effects via regulation of mitochondrial biogenesis, antioxidant defenses, and proteostasis

Each compound has been examined independently in published preclinical literature