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Urinary creatinine was determined using an enzymic kit (LABTEST

Documented total vitamin B12 levels less than 250 pmol/L within the past three months

7 8 NAC's effectiveness as a glutathione precursor does not require high plasma NAC concentrations: once cysteine reaches the target cell, the synthesis machinery uses it efficiently

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However, some confounders affect the predictive value of the PT in the development of hepatotoxicity * : Concurrent anticoagulant use

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