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Mistreat it during reconstitution and it unfolds

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By binding to IGF-1R, IGF-1 can affect metabolism, cell growth (hypertrophy), differentiation and cell division (hyperplasia), prevention of cell death (apoptosis), normal development, and even malignant growth

doi: 10.3389/fimmu.2021.578386 245 HuangJZhangJWangXJinZZhangPSuHet al