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These include increased oxidative stress, environmental exposures, chronic stress, poor sleep, nutritional gaps, and the natural ageing process

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NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

The survey achieved a high response rate of 97.6% for households and 96.7% for eligible women

Additionally, the expression of mRNA and protein for both 25-hydroxylases (CYP2R1 and CYP27A1), 1--hydroxylase (CYP27B1), and VDR were downregulated, but that of 24-hydroxylase (CYP24A1) was significantly upregulated in the liver of HFD-fed mice compared to those in controls (Fig