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The expression plasmid pCGPx3M encoding the human GPx3 mutant was constructed by subcloning the Nde I/ Hin d III fragment from pUC57-GPx3M into the Nde I/ Hin d III sites of the pCold I vector (TaKaRa)

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The compound is not approved by any regulatory authority, and its safety or effectiveness in humans has not been established

And actually I think I was a co-author of that study of that study you're referring to, if it's the one by Tom Sedlak and Akira Sawa and others