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MK-677 also has the advantage of being stable in room temperature, orally bioavailable, sustaining elevated IGF-1 levels 24 hours post-ingestion, and works via stimulating natural endogenous GH secretion, as opposed to exogenous synthetic GH injections which will increase serum GH levels irrespective of the body's current endogenous production without a feedback loop to regulate that hormone levels stay within healthy limits

Wang B, Ma Y, Kong X, Ding X, Gu H, Chu T, Ying W (2014) NAD+ administration decreases doxorubicin-induced liver damage of mice by enhancing antioxidation capacity and decreasing DNA damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 209

Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance

The short answer is: Be careful with layering

GHK-Cu (copper peptide) represents another potential combination partner, though for different applications