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Circulating MOTS-c is detectable in humans and declines with age, but no completed human trial of administered MOTS-c has read out

More clinical research should investigate the effectiveness across different patient conditions, but the existing evidence suggests the treatments are generally safe, well tolerated, and worth trying for those struggling with chronic pain or steroid side effects

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Less Numbness or Tingling This is usually a slower change

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Tingling sensations or numbness in extremities may occur if pyridoxine is taken in very high doses, potentially affecting nerve function adversely