Springer, 39-51, 2013
Graphical Abstract Similar content being viewed by others Introduction Retinitis pigmentosa (RP) is a genetic disorder affecting approximately 1 in 4,000 individuals that leads to loss of photoreceptors and decrease in visual acuity [1, 2]
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Annu Rev Immunol (2016) 34:33568
D.Oropesa-AvilaM.VegaA
Chronic hyperglycemia initiates a cascade of molecular eventsincluding the accumulation of advanced glycation end products (AGEs), activation of the polyol pathway, enhanced protein kinase C (PKC) signaling, and mitochondrial dysfunctionculminating in glomerular hyperfiltration, podocyte injury, and progressive glomerular and tubulointerstitial fibrosis