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However, the current evidence remains largely experimental , and robust human clinical trials are still needed before BPC-157 can be considered an established medical therapy

The TLR1/2 agonist protospacer adjacent motif 3 (PAM3)CSK4 induces the differentiation of human and mouse monocytes into immunosuppressive M2 macrophages, suggesting that PAM3CSK4 may contribute to the prevention of colitis (Horuluoglu et al., 2020)

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2019 doi: 10.1016/j.clnu.2019.05.004