Of note, pharmacologically induced PFC NMDAR hypofunction leads to increased oscillations [99] while genetic deletion of NMDAR1 subunits in pyramidal neurons increases oscillations, cell excitability and sEPSC frequency [100], similar to the present data
GSH additionally plays a multifaceted role in cellular defense, primarily by reducing oxidative stress and facilitating detoxification (Figure 3)
K., Parsanathan, R., Achari, A
Masubuchi Y, Nakayama J, Watanabe Y
Biochem J 446:333348 Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
After repeated washing the bound fraction was eluted with 250 mM imidazole (Fischer) in lysis buffer containing 10% glycerol (Acros)