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Besides their role in mediating lipid peroxidation, ROS especially nitric oxide (NO ), and OH (92), have also been shown to attach to sperm DNA molecules causing excessive modifications and deletions in their nucleotide bases and strand breakages, along with other multiple genotoxic effects (93)

The mechanisms underlying its hepatotoxic effects involve mitochondrial dysfunction, oxidative stress, and the inhibition of the bile salt export pump, resulting in the accumulation of toxic bile salts within hepatocytes [39]

J Mammary Gland Biol Neoplasia, 2020

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The application of probiotics has expanded significantly beyond traditional nutrition, emerging as a bioactive frontier in dermatological and pharmaceutical sciences (137)