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PMC 2756298

10.26355/eurrev_202202_27981 6 AlotaykL

Type I interferons in autoimmunity

IFNs bind to cell surface receptors that are associated with janus kinases (JAK), which then phosphorylate intracellular receptor chains, generating docking sites for the signal transducer and activator of transcription (STAT

This dynamic process ensures tissues are well-nourished and optimally supported for rapid healing, even in challenging scenarios such as ischemic injuries ( 5 )