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doi: 10.1016/j.bbi.2018.12.013 224 MeierJ.TewarieP.HillebrandA.DouwL.van DijkB

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For example, the antioxidant response factor NRF2, a bZIP transcription factor that heterodimerizes with small Maf proteins to bind to the AREs, can be targeted by a chimeric molecule termed 'ARE-PROTAC', which successfully induced simultaneous degradation of the NRF2-MafG complex and synergistically suppressed Nrf2 signaling (229)

Metallomics: Integrated Biometal Science , 16

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