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Nencini C, Giorgi G, Micheli L

NAC supplementation has been studied for heavy metal detoxification, with some evidence of benefit for mercury and lead excretion, though clinical trials are limited [37]

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it is linked to regulation of cortisol and ACTH, potentially normalizing HPA axis function

Not everyone notices dramatic improvements, and a few people question whether some benefits might be partially placebo-driven

After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)