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GCLC and GCLM together form the rate-limiting enzyme in glutathione synthesis, glutamate cysteine ligase

An extensive review of these therapies is outside the scope of this paper, however, the authors direct readers to several published reviews [164168]

2.4.4 Serum full-spectrum metabolism-LCMS metabolomics analysis 2.4.4.1 Pre-treatment (1) Remove the samples stored at -80C, thaw in an ice-water mixture, and pipette 100 L of sample into a 1.5 mL EP tube

Aquaporin-4 expression switches from white to gray matter regions during postnatal development of the central nervous system

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The secondary endpoints include achievement of 20% weight reduction, relative change in body weight, change in waist circumference, change in HbA1c, change in systolic blood pressure, change in the quality of life (IWQOL-Lite-CT), and change in short-form physical functioning score (SF-36v2)