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In addition, Nrf2 can also regulate the expression of downstream enzymes such as GST and GR, further improving the cell's antioxidant defense network and enabling cells to more effectively respond to damage caused by oxidative stress

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Phytotherapy Research, 33 (12), 30903111

The quercetin-hyperoside mixture decreased the amount of crystal deposits in kidney tissue compared with potassium citrate, and antioxidant enzyme activity was increased (Zhu 2014)

2006;291(5):E1044-E1050 Fredriksson K

The thing is that youve got to prove their safety and efficacy in clinical trials before widespread marketing and use