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Furthermore, emerging evidence suggests that melittin inhibits fungal growth via several processes, such as membrane permeability and apoptotic activation via the ROS-induced mitochondrial/caspase-dependent route, suppression of (1,3)-D-glucan synthase, and alterations in fungus genetic transcription

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[DOI] [PMC free article] [PubMed] [Google Scholar] Kim H

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Maintenance phase: settle at the lowest dose that delivers the desired effect